Human retinal endothelial cells express functional interleukin-6 receptor
Abstract Background Interleukin (IL)-6 is an inflammatory cytokine present in the eye during non-infectious uveitis, where it contributes to the progression of inflammation.There are two major IL-6 signaling pathways: classic signaling and trans-signaling.Classic signaling requires cellular expression of the IL-6 receptor (IL-6R), which exists in m